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Potential Side Effects and Safety Considerations of Zinc Magnesium Aspartate - Genetic Nutrition

Potential Side Effects and Safety Considerations of Zinc Magnesium Aspartate

, by Sandesh Prasannakumar, 8 min reading time

Introduction

It affects one’s body in many ways since it has minerals such as zinc and magnesium that are significant in almost all body processes. Zinc is useful for the functioning of the immune system, the synthesis of proteins, the synthesis of DNA and replication. Magnesium is involved in muscle and nerve signal transmission, glucose control and regulation of blood pressure.


The supplement available in the market in the form of Zinc magnesium aspartate is a well-known form that is claimed to deliver the features of zinc and magnesium in the most absorbent structure. The aspartate ligand is supposed to facilitate the transfer of the said minerals across the intestinal wall and to be superior to other forms like zinc oxide or magnesium oxide.


As for side effects, zinc and magnesium aspartate supplements have been reported to be rather safe when taken with the right dosage. However, there are some key side effects for which we should be cautious and some safety concerns.


Common Side Effects

Some of the top complaints made by users of zinc magnesium aspartate are usually symptoms of discomfort in the digestive system. In some people, supplements may cause:

  • Nausea
  • Stomach pain
  • Diarrhea
  • Vomiting

Such problems are generally resolved with time if the supplementation has ceased. They are more likely to occur if high doses are taken, such as in the case of the tics observed in children who are administered the drug. To avoid side effects, the initial dosage is as low as 10-20 mg of zinc and 100-200 mg of magnesium.


Even though zinc magnesium aspartate has intense effects, it is advisable to take it with food and not on an empty stomach to avoid digestive issues. If you continue with the same problem, you may opt for other forms, such as zinc gluconate or magnesium citrate.


Other Possible Side Effects

Less common side effects may include:

  • Unpleasant metallic taste
  • Loss of appetite
  • Headache
  • Dizziness

Having a high amount of zinc in the long term may lead to a copper deficiency since these elements compete for absorption. This is why many zinc supplements, such as zinc magnesium aspartate, have a small amount of copper incorporated in them.


Safety Considerations and Interactions

Zinc and magnesium are found to be effective when taken as supplements in moderation for most people. Those more at risk for side effects or interactions typically include:

  • So, in general, individuals with gastrointestinal diseases.
  • Patients with chronic conditions such as diabetes or those under long-term medication such as antibiotics or antacids
  • It is also important to know that it is not suitable for people with impaired kidney function.

Furthermore, the patients should be aware that zinc can affect other drugs, such as quinolone or tetracycline, if there are not enough hours between the taken doses. Supplementation with zinc and magnesium in quantities above basal needs may also contribute to decreased bioavailability of certain drugs.


To avoid these concerns, it is recommended not to exceed the Tolerable Upper Intake Levels (UL), which indicates that more than 40 mg of zinc from supplements daily and more than 350 mg of magnesium from supplements daily should not be taken without consulting a doctor. Furthermore, one should always disclose information to one’s healthcare provider in regard to supplements consumed.


The Bottom Line

As for the majority of healthy consumers, zinc and magnesium aspartate show great tolerance and don’t cause hazardous effects if the right dosage is taken and strict adherence to the taken measures is followed. Diarrhea, rarely, is one of the possible side effects that are associated with the use of this medicine. Though the side effects are not likely severe, it is wise to tread carefully with supplementation and consult your doctor for any potential health complications or medications that may increase your risk or change your dosage. Overall, flexibility, realistic goal setting, and the ability to wait for something better if the first attempt does not yield the desired results are important to getting a good result.

For all your protein and supplement needs, visit Genetic Nutrition!

Frequently Asked Questions

1. Is it true that Zinc and Magnesium Aspartate have side effects if one takes them daily?

Mild side effects such as nausea, stomach discomfort, and diarrhoea are also common, but these usually arise from overly high starting doses. Small doses of 10-20 mg of zinc and 100-200 mg of magnesium can help avoid negative reactions in the organism. It is noteworthy that the majority of individuals feel comfortable with daily supplementation as long as proper dosage is employed.


2. Is it safe to use ZMA for the long term?

Yes, those with low zinc and magnesium intakes from their diets can safely take zinc aspartate supplements for long-term use. To avoid the potential adverse effect of high zinc consumption, which may hurt the long-term copper status, select formulas with approximately 1-2 µg of copper. Moreover, do not regularly exceed the following ULs: 40mg for zinc and 350mg for magnesium.


3. What side effects will I get when using zinc magnesium aspartate? 

Zinc & magnesium should not be consumed simultaneously with some medications, such as antibiotics or heart medications. It is also important to note that the high doses may be less effective for patients with renal malfunction or those with certain gastrointestinal diseases that may hinder nutrient assimilation. It is always recommended to consult your doctor first before taking supplements to avoid any complications, especially if you are on some common prescription drugs or have some chronic illnesses.


4. What is the correct dosage, or how can zinc magnesium aspartate be used without having some digestive side effects?

Beginning with such doses will reduce the likelihood of side effects — zinc should be taken in 10-20mg, and magnesium in 100-200 mg. You may also find that taking your dose with a meal rather than between meals can help. The consumer should follow the instructions on the packet and consult the physician if the side effects do not disappear. If you still experience substantial gastrointestinal distress, it might be helpful to experiment with a different form of supplementation.

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